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What the FDA Relabeling of Abacavir Means for You and Your Patient



HLA-B*5701 Correlations

Slide 11

November 2008

The HLA-B*5701 allele is involved in hypersensitivity reaction with abacavir in 5-8% of patients who initiate therapy. Prevalence of the HLA-B*5701 allele varies among racial groups; however, the point is it is present in all racial and ethnic groups that have been tested to some extent. Consequently, all patients who are going to be receiving this drug should be tested for this specific allele. And there are very high odds ratio for abacavir hypersensitivity reaction when the patient carries the HLA-B*5701 allele.

HLA-B*5701 Correlations

 


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