Preanalytic Variables in Special Coagulation Testing

Introduction

October 2008

Welcome to Mayo Medical Laboratories' Hot Topics. These presentations provide short discussions of current topics and may be helpful to you in your practice.

Proper processing and handling of specimens for coagulation testing is essential to ensure specimen integrity and accurate test results. Dr. Pruthi uses a case-based presentation to discuss the clinical implications of selected preanalytic variables in special coagulation testing and interpretation.

Introduction

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Jump to section:

• Variables Affecting Test Results
• Preanalytic Variables Affecting Coagulation Testing
• Special Coagulation Test Algorithms
• Case History
• Preprocedure Coagulation Tests
• PT and aPTT Diagram
• Normal Hematocrit and High Hematocrit
• Preprocedure Coagulation Tests
• Case Conclusion
• Case Example
• Repeat Testing With Fresh Sample
• Intrinsic and Extrinsic Diagram
• Clotted Specimen: Definition of Clotted Specimen
• Significance of Clotted Specimen
• Significance of Clotted Specimen
• Preanalytic Factors Affecting Testing Results: Clotted Specimen
• Scope of the Problem
• Event Capture Tool
• Clotted Specimens as a Percentage of Test Volume
• Clotted Specimens 2007
• Clinical Laboratory Standards Institute
• Rejection of Specimen: Impact
• Causes of Clotted Specimen
• Steps Towards Reducing Clotted Specimens
• Conclusion
• Questions?