Preanalytic Variables in Special Coagulation Testing

Preprocedure Coagulation Tests

October 2008

So when that sample is analyzed, the amount of added assay or calcium is insufficient to activate the coagulation cascade, thus resulting in an artifactually prolonged PT and our aPTT.

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Preprocedure Coagulation Tests

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Jump to section:

• Introduction
• Variables Affecting Test Results
• Preanalytic Variables Affecting Coagulation Testing
• Special Coagulation Test Algorithms
• Case History
• Preprocedure Coagulation Tests
• PT and aPTT Diagram
• Normal Hematocrit and High Hematocrit
• Preprocedure Coagulation Tests
• Case Conclusion
• Case Example
• Repeat Testing With Fresh Sample
• Intrinsic and Extrinsic Diagram
• Clotted Specimen: Definition of Clotted Specimen
• Significance of Clotted Specimen
• Significance of Clotted Specimen
• Preanalytic Factors Affecting Testing Results: Clotted Specimen
• Scope of the Problem
• Event Capture Tool
• Clotted Specimens as a Percentage of Test Volume
• Clotted Specimens 2007
• Clinical Laboratory Standards Institute
• Rejection of Specimen: Impact
• Causes of Clotted Specimen
• Steps Towards Reducing Clotted Specimens
• Conclusion
• Questions?