Preanalytic Variables in Special Coagulation Testing
Clinical Implications
Case History

October 2008
In order to illustrate the impact on selected preanalytical variables on patient management, we will show two illustrated cases.
In this case, a 47-year-old male, with a complex cyanotic congential heart disease, which consisted of a single ventricle with transposition of great vessels and severe pulmonary hypertension, was seeing his cardiologist for a follow-up.
His cardiologist was planning a cardiac angiogram. Given the patient’s cyanotic congenital heart disease his hematocrit was markedly elevated as shown.
Case History |
Jump to section:
- Introduction
- Variables Affecting Test Results
- Preanalytic Variables Affecting Coagulation Testing
- Special Coagulation Test Algorithms
- Case History
- Preprocedure Coagulation Tests
- PT and aPTT Diagram
- Normal Hematocrit and High Hematocrit
- Preprocedure Coagulation Tests
- Case Conclusion
- Case Example
- Repeat Testing With Fresh Sample
- Intrinsic and Extrinsic Diagram
- Clotted Specimen: Definition of Clotted Specimen
- Significance of Clotted Specimen
- Significance of Clotted Specimen
- Preanalytic Factors Affecting Testing Results: Clotted Specimen
- Scope of the Problem
- Event Capture Tool
- Clotted Specimens as a Percentage of Test Volume
- Clotted Specimens 2007
- Clinical Laboratory Standards Institute
- Rejection of Specimen: Impact
- Causes of Clotted Specimen
- Steps Towards Reducing Clotted Specimens
- Conclusion
- Questions?


