Preanalytic Variables in Special Coagulation Testing
Clinical Implications
Special Coagulation Test Algorithms
October 2008
Commonly ordered coagulation test include prothrombin time (PT) and activated partial thromboplastin time (aPTT). Additional specialized assays include individual clotting factor assays, and assays for anticoagulant proteins such as protein C and antithrombin.
DNA-based on molecular tests are not based on the clotting assays, such as the PT and aPTT, and have a different set of preanalytical variables affecting results.
Special Coagulation Test Algorithms |
Jump to section:
- Introduction
- Variables Affecting Test Results
- Preanalytic Variables Affecting Coagulation Testing
- Special Coagulation Test Algorithms
- Case History
- Preprocedure Coagulation Tests
- PT and aPTT Diagram
- Normal Hematocrit and High Hematocrit
- Preprocedure Coagulation Tests
- Case Conclusion
- Case Example
- Repeat Testing With Fresh Sample
- Intrinsic and Extrinsic Diagram
- Clotted Specimen: Definition of Clotted Specimen
- Significance of Clotted Specimen
- Significance of Clotted Specimen
- Preanalytic Factors Affecting Testing Results: Clotted Specimen
- Scope of the Problem
- Event Capture Tool
- Clotted Specimens as a Percentage of Test Volume
- Clotted Specimens 2007
- Clinical Laboratory Standards Institute
- Rejection of Specimen: Impact
- Causes of Clotted Specimen
- Steps Towards Reducing Clotted Specimens
- Conclusion
- Questions?
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