Preanalytic Variables in Special Coagulation Testing
Clinical Implications
Causes of Clotted Specimen

October 2008
We attempted to determine potential patient variables that may influence clotted specimens, so we looked at the type of test that were ordered on the specimens that were found to be clotted. As an example, we tried to determine the type of test ordered, by that I mean we looked into whether these clotted samples had thrombosis profiles or components; or bleeding profiles or components ordered. We found no trend toward one type of order or another, making individual patient variables less likely.
It is well-established that optimal sample collection and processing is key to avoiding clotted specimens, however; this would be a daunting study to do given the numerous client laboratories and technologists involved.
Causes of Clotted Specimen |
Jump to section:
- Introduction
- Variables Affecting Test Results
- Preanalytic Variables Affecting Coagulation Testing
- Special Coagulation Test Algorithms
- Case History
- Preprocedure Coagulation Tests
- PT and aPTT Diagram
- Normal Hematocrit and High Hematocrit
- Preprocedure Coagulation Tests
- Case Conclusion
- Case Example
- Repeat Testing With Fresh Sample
- Intrinsic and Extrinsic Diagram
- Clotted Specimen: Definition of Clotted Specimen
- Significance of Clotted Specimen
- Significance of Clotted Specimen
- Preanalytic Factors Affecting Testing Results: Clotted Specimen
- Scope of the Problem
- Event Capture Tool
- Clotted Specimens as a Percentage of Test Volume
- Clotted Specimens 2007
- Clinical Laboratory Standards Institute
- Rejection of Specimen: Impact
- Causes of Clotted Specimen
- Steps Towards Reducing Clotted Specimens
- Conclusion
- Questions?


