Preanalytic Variables in Special Coagulation Testing
Clinical Implications
Significance of Clotted Specimen
October 2008
As I indicated before, in addition to containing clotting factors, plasma also contains the anticoagulant factors. So, the clotting process consumes clotting factors to form the fibrin clot. This results in prolongation of clotting times such as the PT and aPTT, and if assayed results in reduced clotting factors.
Significance of Clotted Specimen |
Jump to section:
- Introduction
- Variables Affecting Test Results
- Preanalytic Variables Affecting Coagulation Testing
- Special Coagulation Test Algorithms
- Case History
- Preprocedure Coagulation Tests
- PT and aPTT Diagram
- Normal Hematocrit and High Hematocrit
- Preprocedure Coagulation Tests
- Case Conclusion
- Case Example
- Repeat Testing With Fresh Sample
- Intrinsic and Extrinsic Diagram
- Clotted Specimen: Definition of Clotted Specimen
- Significance of Clotted Specimen
- Significance of Clotted Specimen
- Preanalytic Factors Affecting Testing Results: Clotted Specimen
- Scope of the Problem
- Event Capture Tool
- Clotted Specimens as a Percentage of Test Volume
- Clotted Specimens 2007
- Clinical Laboratory Standards Institute
- Rejection of Specimen: Impact
- Causes of Clotted Specimen
- Steps Towards Reducing Clotted Specimens
- Conclusion
- Questions?
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