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Preanalytic Variables in Special Coagulation Testing

Clinical Implications

Case Example

Slide 11

October 2008

The next case is one of a 45 year-old male referred to our hemophilia center for evaluation of diagnosis of mild congenital hemophilia. He had undergone a dental extraction and had more then expected hemorrhage lasting for about a week.

He was tested locally, where von Willebrand factor antigen and ristocetin co-factor activity when noted to be normal; however, Factor VIII was mildly reduced. He brought in his outside medical records and next to the Factor VII results there was an asterisk indicating that a clot was noted in the specimen tube.

Case Example


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