Chronic Lymphocytic Leukemia
New Approaches for a Common Disease
CLL MRD Case: Clinical History

October 2008
I want to close my talk by sharing a brief case of a CLL with minimal residual disease. This was a 58 year-old lady who approximately 9 years ago was diagnosed with CLL on the basis of her peripheral blood lymphocytosis and a diagnostic flow study. No organomegaly and no cytopenias were present. She was called a Rai Stage 0 CLL and was not treated.
CLL MRD Case: Clinical History |
Jump to section:
- Introduction
- Goals Today
- CLL, MBL, and SLL Overview
- CLL: Evolution of Diagnostic Criteria
- Chronic B-Cell Lymphoproliferative Disorders: Prototypic Immunophenotype
- CLL: Dim sIg, dim CD20, CD5+ & CD23+
- "Copycat": MCL with CD5+/partial CD23+
- "Copycat": LPL with CD5+/CD23-
- Diagnosis of MBL & SLL: IWCLL
- Diagnostic Criteria: CLL, MBL, and SLL
- Diagnostic Criteria: CLL, MBL, and SLL
- Identification of MBL
- How will MBL be Recognized in Routine Clinical Practice?
- How is MBL Recognized in Routine Clinical Practice?
- Diagnostic Criteria: MBL in Clinical Practice
- MBL: Prevalence and Progression
- MBL: Summary
- Familial CLL
- MBL Case: Clinical History
- MBL Case: Peripheral Blood Immunophenotype
- MBL Case: Bone Marrow Biopsy
- Diagnosis Diagram
- CLL and Minimal Residual Disease (MRD)
- CLL and Minimal Residual Disease (MRD)
- CLL and Minimal Residual Disease (MRD)
- CLL MRD Case: Clinical History
- CLL MRD Case: Clinical History
- CLL MRD Case: Bone Marrow Biopsy
- CLL MRD Case: Bone Marrow Biopsy
- CLL MRD Case: PB Flow
- CLL MRD Case: BM Flow
- Goals Today
- Questions?


