Laboratory Testing for Hepatitis A and E

Summary Hepatitis A

September 2008

In summary, Hepatitis A diagnosis requires a high index of suspicion in patients with epidemiologic exposure history. Hepatitis A IgM positive results must be correlated carefully with clinical findings and epidemiologic exposure history because of the frequency of false-positive results.

The presence of Hepatitis A-specific total antibodies in individuals who are non-symptomatic usually represent past infection or vaccination with the Hepatitis A vaccine.

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Summary Hepatitis A

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Jump to section:

• Introduction
• Patient Case
• Geographic Distribution of Hepatitis A Virus Infection
• Hepatitis A Epidemiology
• Hepatitis A Virus Infection Typical Serologic Course
• Hepatitis A Diagnosis
• Assay Methods for HAV Serologic Markers
• Patient Case
• Interpretation of HAV Serologic Marker Test Results
• Patient Case
• Incidence of Acute Hepatitis A by Year
• Incidence of Acute Hepatitis A by Age
• Trends in Epidemiologic Characteristics
• Incidence of Acute Hepatitis A by Race/Ethnicity
• Geographic Distribution of Hepatitis E
• Hepatitis E Epidemiology
• Hepatitis E Virus Infection
• Hepatitis E Diagnosis
• Summary Hepatitis A
• Summary Hepatitis E
• Questions?
• Disclosure