Laboratory Testing for Hepatitis A and E

Hepatitis E Diagnosis

September 2008

Diagnosis of Hepatitis E is again confirmed by serologic testing. As you can see from this table, acute Hepatitis A is confirmed by the presence of Hepatitis A-specific IgM antibody whereas past infection is defined by the presence of Hepatitis A-specific IgG antibody. However, a note of caution is needed here because in populations with low prevalence of Hepatitis A infection, such as North America, Hepatitis A IgM results are frequently falsely-positive due to the low positive predictive value of this test in such low-prevalence populations.

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Hepatitis E Diagnosis

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Jump to section:

• Introduction
• Patient Case
• Geographic Distribution of Hepatitis A Virus Infection
• Hepatitis A Epidemiology
• Hepatitis A Virus Infection Typical Serologic Course
• Hepatitis A Diagnosis
• Assay Methods for HAV Serologic Markers
• Patient Case
• Interpretation of HAV Serologic Marker Test Results
• Patient Case
• Incidence of Acute Hepatitis A by Year
• Incidence of Acute Hepatitis A by Age
• Trends in Epidemiologic Characteristics
• Incidence of Acute Hepatitis A by Race/Ethnicity
• Geographic Distribution of Hepatitis E
• Hepatitis E Epidemiology
• Hepatitis E Virus Infection
• Hepatitis E Diagnosis
• Summary Hepatitis A
• Summary Hepatitis E
• Questions?
• Disclosure