Antibodies Against Citrullinated Peptides
A Role in the Diagnosis of Rheumatoid Arthritis
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Introduction
September 2008
Welcome to Mayo Medical Laboratories' Hot Topics. These presentations provide short discussions of current topics and may be helpful to you in your practice.
Our presenter for this program is Dr. Melissa Snyder, Director of the Antibody Immunology Laboratory, in the Division of Clinical Biochemistry and Immunology at Mayo Clinic. Dr. Snyder discusses the use of anti-citrulline antibody in the Mayo connective tissue disease cascade algorithm to improve the specificity for diagnosis of rheumatoid arthritis.
Introduction |
Jump to section:
- Introduction to Connective Tissue Diseases
- Clinical Symptoms of Rheumatoid Arthritis
- Epidemiologic Features of Rheumatoid Arthritis
- Diagnostic Criteria for Rheumatoid Arthritis
- Utility of Rheumatoid Factor
- Discovery of Anti-Citrulline Antibodies
- Enzymatic Process of Citrullination
- Diagnostic Performance of Anti-Citrulline Antibodies
- Development of Clinical Assays for Anti-Citrullinated Protein Antibodies
- Development of Clinical Assays for Anti-Citrullinated Protein Antibodies
- Sensitivity and Specificity Comparison Anti-CCP and RF
- Diagnostic Algorithm for CTDs
- Summary
- Questions?
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