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Antibodies Against Citrullinated Peptides

A Role in the Diagnosis of Rheumatoid Arthritis



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Clinical Symptoms of Rheumatoid Arthritis

Slide 3

September 2008

As I just stated, Rheumatoid Arthritis is a systemic disease. In most individuals, the disease begins as articular manifestations generally as a polyarthritis. This process begins with inflammation within the synovial joint. Ultimately, without adequate treatment the disease may progress to erosion and destruction of the cartilage and bone within the joint. 

In some pts, the disease progresses beyond the joint.  Some of the more common extra-articular manifestations include the development of nodules, osteoporosis, and vasculitis. Some individuals may develop rheumatoid lung disease and cardiac disease as well.

Clinical Symptoms of Rheumatoid Arthritis

 


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