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Warfarin Sensitivity Genotyping

Warfarin Monitoring

Slide 5

August 2008

Warfarin anticoagulation is monitored by measuring the prothrombin time (PT) and calculating the international normalized ratio (INR). In this particular case the INR equals the ratio of the patient prothrombin time normalized to the mean prothrombin time of a control group in your clinical setting and that is raised to the power of the international sensitivity index which takes into consideration of the availability of the thromboplastin used by the manufacturer of the kit.

Warfarin has a very narrow window for dosing. The best target for the INR for most patients is between 2 and 3.

Warfarin Monitoring


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