Free Light Chains & Monoclonal Gammopathies
Impact on Diagnostic Panels
Serum Protein Electrophoresis & Immunofixation Electrophoresis
August 2008
In this next slide, illustrates the analysis of serum from a patient with light chain multiple myeloma. We see that PEL has only a minimally abnormal pattern and the IFE has a small amount of monoclonal lambda light chain. Although this is a myeloma, it is very different from the IgG kappa seen on the previous slide.
Serum Protein Electrophoresis |
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- Introduction
- Diagnostic Tests
- Mayo Clinic 1960-2003
- Plasma Cell Proliferative Disorders
- Serum Protein Electrophoresis & Immunofixation Electrophoresis
- Serum Protein Electrophoresis & Immunofixation Electrophoresis
- Monoclonal Serum Proteins: Newly Diagnosed Multiple Myeloma (n=1027)
- Serum Protein Electrophoresis & Immunofixation Electrophoresis
- Urine Protein Electrophoresis & Immunofixation Electrophoresis
- Intact Immunoglobulin/Free Light Chain
- FLC Reference Range
- Diagnoses for 428 Patients Selected for Urine Monoclonal Protein
- Serum PEL & IFE Results: 428 Pts with Urine Monoclonal Protein
- Laboratory Results: 428 Patients with Monoclonal Urinary Protein
- Potential Savings
- Uses of Serum Free Light Chain Assay
- Diagnostic Test Panel for Suspected Monoclonal Gammopathies
- Questions?
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