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Free Light Chains & Monoclonal Gammopathies

Impact on Diagnostic Panels

Monoclonal Serum Proteins: Newly Diagnosed Multiple Myeloma (n=1027)

Slide 7

August 2008

Although Multiple Myeloma is a malignancy with a large number of colonel plasma cells and should be easy to detect by these assays. This slide points out the problem. Approximately, 75% of myeloma patients secrete intact immunoglobulins that will have large M-spikes. But approximately, 25% secrete only light chains or nothing at all.

Monoclonal Serum Proteins


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