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Free Light Chains & Monoclonal Gammopathies

Impact on Diagnostic Panels

Mayo Clinic 1960-2003

Slide 3

August 2008

There are at least a dozen different plasma cell proliferative disorders. On this slide I’ve listed the incidents of these in our Mayo Clinic practice. By far the most common disorder is monoclonal gammopathy of undetermined significance or MGUS. This is a premalignant condition and has no clinical symptoms; no anemia, no renal disease, no bone lesions. This is followed in incidence by other diseases such as multiple myeloma or primary amyloidosis or macroglobulinemia. All of these diseases listed here will have different clinical presentations and may require different treatments.

Mayo Clinic 1960-2003


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