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Free Light Chains & Monoclonal Gammopathies

Impact on Diagnostic Panels



Diagnostic Test Panel for Suspected Monoclonal Gammopathies

Slide 17

August 2008

So in summary and in conclusion, we recommend using serum protein electrophoresis, immunofixation electrophoresis and free light chain quantitation as the initial diagnostic screening panel for patients suspected of having a plasma cell proliferative disorder. This panel provides sufficient diagnostic sensitivity without the need for urine studies.

In addition if the patient does indeed have a monoclonal gammopathy, this panel provides prognostic information in many plasma cell proliferative disorders. And lastly, if there is no M-spike the serum free light chain assay may provide a quantitative value for disease monitoring.

Diagnostic Test Panel

 


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