Free Light Chains & Monoclonal Gammopathies
Impact on Diagnostic Panels
Laboratory Results: 428 Patients with Monoclonal Urinary Protein
August 2008
If we now include the serum free light change in our analysis, on this slide we see that the combination of serum, protein electrophoresis, immunofixation electrophoresis and free light chain quantitation detect almost all of the patients detected by urine studies, only 2 patients out of 428 were missed and neither required intervention. And this has led us to conclude that we should add serum free light chain to our diagnostic screen and eliminate urine studies from this initial testing.
Laboratory Results |
Jump to section:
- Introduction
- Diagnostic Tests
- Mayo Clinic 1960-2003
- Plasma Cell Proliferative Disorders
- Serum Protein Electrophoresis & Immunofixation Electrophoresis
- Serum Protein Electrophoresis & Immunofixation Electrophoresis
- Monoclonal Serum Proteins: Newly Diagnosed Multiple Myeloma (n=1027)
- Serum Protein Electrophoresis & Immunofixation Electrophoresis
- Urine Protein Electrophoresis & Immunofixation Electrophoresis
- Intact Immunoglobulin/Free Light Chain
- FLC Reference Range
- Diagnoses for 428 Patients Selected for Urine Monoclonal Protein
- Serum PEL & IFE Results: 428 Pts with Urine Monoclonal Protein
- Laboratory Results: 428 Patients with Monoclonal Urinary Protein
- Potential Savings
- Uses of Serum Free Light Chain Assay
- Diagnostic Test Panel for Suspected Monoclonal Gammopathies
- Questions?
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