Free Light Chains & Monoclonal Gammopathies
Impact on Diagnostic Panels
Diagnoses for 428 Patients Selected for Urine Monoclonal Protein
August 2008
This slide illustrates how we tested this hypothesis. We identified 428 patients with the monoclonal protein in the urine, and who also had serum studies that included PEL, IFE and free light chain. We wanted to test whether this combination of serum assays would detect all these patients with abnormal urine studies. This slide lists the distribution of diagnosis of this cohort, approximately one-third have multiple myeloma, approximately one-third have primary amyloidosis and approximately one-third have premalignant conditions of MGUS or smoldering multiple myeloma.
Diagnoses for Patients |
Jump to section:
- Introduction
- Diagnostic Tests
- Mayo Clinic 1960-2003
- Plasma Cell Proliferative Disorders
- Serum Protein Electrophoresis & Immunofixation Electrophoresis
- Serum Protein Electrophoresis & Immunofixation Electrophoresis
- Monoclonal Serum Proteins: Newly Diagnosed Multiple Myeloma (n=1027)
- Serum Protein Electrophoresis & Immunofixation Electrophoresis
- Urine Protein Electrophoresis & Immunofixation Electrophoresis
- Intact Immunoglobulin/Free Light Chain
- FLC Reference Range
- Diagnoses for 428 Patients Selected for Urine Monoclonal Protein
- Serum PEL & IFE Results: 428 Pts with Urine Monoclonal Protein
- Laboratory Results: 428 Patients with Monoclonal Urinary Protein
- Potential Savings
- Uses of Serum Free Light Chain Assay
- Diagnostic Test Panel for Suspected Monoclonal Gammopathies
- Questions?
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