Serologic Testing for Rubella
Because of this, Mayo Medical Laboratories has discontinued all serologic testing for IgM-class antibodies to Rubella. This decision was based on several factors, including:
- The absence of endemic transmission of the disease in the United States as determined by the CDC;
- The high rate of vaccine coverage (>95%) among school-aged children;
- The high level of immunity in this country; and finally,
- The potential negative impact of false-positive Rubella IgM result.
Although it’s not recommended, Rubella IgM testing is often performed prenatally in asymptomatic pregnant women. In this setting, a false-positive result may generate substantial worry to parents, needless follow-up testing, needless expenditure of resources, and potentially the termination of healthy pregnancies.
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