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Laboratory Testing for Hepatitis B


Slide 8

June 2008

Diagnosis of Hepatitis B should be based on the patient’s medical history, risk of exposure and system complex along with evidence of abnormality in physical examination and other chemistry laboratory tests.

Here is a table of the various combinations of serologic markers for those with acute, chronic carrier or previous infections due to Hepatitis B. Of note is that Hepatitis B core IgM antibody is present only during the acute infection phase and Hepatitis B E antigen can be present or absent during chronic Hepatitis B stage. In the case of the active viral replication of chronic Hepatitis B, the E antigen is positive whereas those with minimal or inactive viral replication but still has positive Hepatitis B surface antigen will have negative E antigen.



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