Laboratory Testing for Hepatitis B
Serologic Methods
June 2008
There are several laboratory testing methods for serologic testing of Hepatitis B. As you can see, the most commonly used is the enzyme immunoassay (EIA) and these are the methods used in the Abbott Commander, Bio-Rad, and Ortho ELISA systems. There is also the micro particle EIA, used by the Abbot AxSYm system.
The most recent advancement in immunoassays for hepatitis serologic testing is the application of chemiluminescence immunoassay (CIA) technology and here you see that the Ortho Vitros, the ADVIA Centaur, and the Immulite 2000 systems utilize this CIA.
The Roche Elecsys 2010 system used an electro-magnetic form of CIA in this assay. The latest system from Abbott, the Architect, uses chemiluminescent micro particle immunoassay.
Serologic Methods |
Jump to section:
- Introduction
- Patient Case
- Patient Case
- Acute HBV Infection with Recovery
- Progression to Chronic HBV Infection
- Serologic Markers
- Serologic Methods
- Diagnosis
- Anti-HBs - Qualitative vs Quantitative
- Anti-HBs - Qualitative vs Quantitative
- Molecular Testing
- HBV DNA Quantification Assays
- Patient Case
- Chronic Hepatitis B Therapeutic Options
- Patient Case
- Virologic Breakthrough During Rx for CHB
- HBV Genotyping and Drug Resistance Tests
- HBV Resistance Mutations
- Patient Case
- Summary
- Questions?
- Disclosure
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