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Laboratory Testing for Hepatitis B

Progression to Chronic HBV Infection

Slide 5

June 2008

For the minority of patients, namely adults who get Hepatitis B infection, they present with this serologic course in which the surface antigen is present and persists for years, and that’s the definition of chronic Hepatitis B or Hepatitis B carrier. The Hepatitis B E antigen is also present and persistent, but eventually, with immune tolerance and resolution of the infection they will convert to anti-Hepatitis B E antibody.

Note that Hepatitis B DNA (shown in the blue bar) is present and persists as long as the surface antigen is positive.

Progression to Chronic HBV


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