Laboratory Testing for Hepatitis B

Patient Case

June 2008

Mayo Medical Laboratories offers two test options for the testing of Hepatitis B. One is the Chronic Hepatitis Profile of Unknown Type, indicated as test number 9025. The other, to be used if chronic Hepatitis B is suspected, is test number 9023.

This particular provider chose the chronic hepatitis profile of unknown type. This patient was found to have a confirmed positive Hepatitis B surface antigen and anti-Hepatitis B core total antibodies with negative surface antibody and negative Hepatitis C antibodies.

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• Introduction
• Patient Case
• Patient Case
• Acute HBV Infection with Recovery
• Progression to Chronic HBV Infection
• Serologic Markers
• Serologic Methods
• Diagnosis
• Anti-HBs - Qualitative vs Quantitative
• Anti-HBs - Qualitative vs Quantitative
• Molecular Testing
• HBV DNA Quantification Assays
• Patient Case
• Chronic Hepatitis B Therapeutic Options
• Patient Case
• Virologic Breakthrough During Rx for CHB
• HBV Genotyping and Drug Resistance Tests
• HBV Resistance Mutations
• Patient Case
• Summary
• Questions?
• Disclosure