Laboratory Testing for Hepatitis B

Patient Case

June 2008

Let’s return to the patient’s case. This patient subsequently was found to have a Hepatitis B DNA level of 8,500,000 IU/mL in serum. This is quantified by the MML test number 88634. The provider also has requested an HBV genotype. She was found to be infected with the genotype b strain of Hepatitis B virus.

This patient was started with Entecavir, which is one of the current FDA-approved antiviral agents for treating chronic Hepatitis B.

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Jump to section:

• Introduction
• Patient Case
• Patient Case
• Acute HBV Infection with Recovery
• Progression to Chronic HBV Infection
• Serologic Markers
• Serologic Methods
• Diagnosis
• Anti-HBs - Qualitative vs Quantitative
• Anti-HBs - Qualitative vs Quantitative
• Molecular Testing
• HBV DNA Quantification Assays
• Patient Case
• Chronic Hepatitis B Therapeutic Options
• Patient Case
• Virologic Breakthrough During Rx for CHB
• HBV Genotyping and Drug Resistance Tests
• HBV Resistance Mutations
• Patient Case
• Summary
• Questions?
• Disclosure