Laboratory Testing for Hepatitis B

Anti-HBs - Qualitative vs Quantitative

June 2008

For quantitative Hepatitis B surface antibody, this test is mainly indicated to determine adequacy of human Hepatitis B immunoglobulin therapy in post-operative liver transplant recipients with chronic Hepatitis B. This titer is helpful for clinicians and pharmacists to determine the optimal dose and dosing interval for HBIG therapy based on clearance of the Hepatitis B surface antibody in the recipient serum.

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Qualitative vs Quantitative

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Jump to section:

• Introduction
• Patient Case
• Patient Case
• Acute HBV Infection with Recovery
• Progression to Chronic HBV Infection
• Serologic Markers
• Serologic Methods
• Diagnosis
• Anti-HBs - Qualitative vs Quantitative
• Anti-HBs - Qualitative vs Quantitative
• Molecular Testing
• HBV DNA Quantification Assays
• Patient Case
• Chronic Hepatitis B Therapeutic Options
• Patient Case
• Virologic Breakthrough During Rx for CHB
• HBV Genotyping and Drug Resistance Tests
• HBV Resistance Mutations
• Patient Case
• Summary
• Questions?
• Disclosure