Serologic Diagnosis of Lyme Disease

Lyme Disease - Diagnostic Approach, cont.

May 2008

In addition to serology I just wanted to mention another diagnostic approach available at Mayo Medical Laboratories that being molecular detection of Borrelia nucleic acid by real-time PCR. This method is available on several specimen types including tissue, synovial fluid, blood and cerebrospinal fluid.  Interestingly we have observed the highest detection rates of Borrelia nucleic acid using this method when testing tissue and synovial fluid and we consider these specimens to be the most optimal sources for testing by Lyme real-time PCR.

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Diagnostic Approach, cont.

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• Introduction
• Patient Case
• Lyme Disease
• Lyme Disease - Diagnostic Approach
• Lyme Disease - Diagnostic Approach, cont.
• Lyme Disease - Diagnostic Approach, cont.
• Patient Case, cont.
• Diagnosis of Lyme Disease
• Lyme Disease - Serologic Assays
• Lyme Disease - Serologic Assays, cont.
• Lyme Disease - Serologic Assays, cont.
• Patient Case, cont.
• Lyme Disease - Serologic Assays, cont.
• Patient Case, cont.
• Lyme Disease - Conclusions
• Questions?