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Serologic Diagnosis of Lyme Disease

Lyme Disease - Diagnostic Approach

Slide 4

May 2008

When a patient presents for evaluation of possible Lyme disease the diagnosis is often clinical and may be based on symptoms and objective clinical findings including the presence of Erythema migrans, facial palsy or arthritis. Laboratory testing is generally not recommended in patients presenting with Erythema migrans as this clinical feature is highly suggestive of Lyme disease. In addition, lab testing should not be performed in patients lacking symptoms, inappropriate exposure history, or in those individuals that reside in a nonendemic region and lack a recent travel history to an endemic region.

Diagnostic Approach


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