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Serologic Diagnosis of Lyme Disease

Lyme Disease - Conclusions

Slide 15

May 2008

In conclusion, the laboratory diagnosis of Lyme disease is most commonly achieved by serologic testing which should be limited to those persons with an appropriate exposure history and objective clinical findings. When serology is ordered, testing should be performed using the two step approach as recommended by the CDC, in which specimens are first tested by a highly sensitive screening method such as EIA with all screen positive or equivocal specimens being tested by Western blot. Finally, the result of Lyme serology should be used to support a clinical diagnosis in those patients being evaluated for Lyme disease.



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