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Von Willebrand Disease (VWD)
Part 4: VWF Multimer Analysis

The Role of von Willebrand Factor Multimer Analysis in Diagnosis

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July 2011

Von Willebrand disease (VWD) is the most common of the inherited bleeding disorders. Plasma von Willebrand factor (VWF) multimer analysis is a qualitative visual assessment of the size spectrum and the banding pattern of VWF. This analysis, in conjunction with other tests of hemostasis, assists in the classification of von Willebrand disease.


  • Rajiv K Pruthi, MBBS, Co-director of the Special Coagulation Laboratory and the Special Coagulation DNA Diagnostic Laboratory and Director of the Comprehensive Hemophilia Center at Mayo Clinic in Rochester, Minnesota.

This is the last in a four-part series on von Willebrand disease, and is also included in the series on test utilization.

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The von Willebrand Disease (VWD) Series

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  • Hematologists
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