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Evaluating Autoimmune Encephalopathies, Dementias, and Epilepsies



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August 2014

A number of disorders of the central nervous system previously considered neurodegenerative and untreatable are now recognized as having a treatable autoimmune cause. Improved recognition is facilitated by an expanding profile of neural-specific autoantibodies and when detected in serum or cerebrospinal fluid, these IgG biomarkers reliably predict an autoimmune cause for neurological dysfunction in patients presenting with rapidly progressive brain disorders. New testing profiles relevant to the evaluation of autoimmune encephalopathy, dementia, and epilepsy are now available at Mayo Clinic.

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