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Cytochrome P450 2D6

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October 2013

Several commonly prescribed drugs are metabolized by the CYP2D6 enzyme. Examples include codeine, tamoxifen, tramadol, and metoprolol. Variations in the CYP2D6 gene causes variations in the function of the enzyme, and therefore in drug metabolism. Dr. Black will explain how identification of specific alleles will assist clinicians in selection of appropriate drugs for each individual.


  • John Logan Black, MD
    • Co-director of the Personalized Genomics Laboratory
    • Consultant in the Department of Laboratory Medicine and Pathology
    • Professor in the College of Medicine

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