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The Region 4 Stork (R4S) Collaborative Project

Part 1: Laboratory Quality Improvement of Newborn Screening



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May 2013

Accurate identification of newborns with metabolic disease can significantly improve patient outcomes. Conversely, a missed diagnosis can result in significant morbidity and may even result in death. While a false-positive diagnosis does not carry the burden of increased morbidity or mortality, there are social and psychological costs that may generate significant harm. The Region 4 Stork Collaborative was developed to improve detection of true positive cases of metabolic disease and improve accurate diagnosis. The R4S project uses Mayo-developed software that provides postanalytical interpretation of complex metabolic profiles. The R4S project offers physicians worldwide the opportunity to utilize this software to analyze their patients’ test results, and compare them with other locations’ results.

Region 4 Stork (R4S) Collaborative Project Part 1 introduces the concept of disease ranges for improved identification of abnormal newborn screening results.

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The Region 4 Stork (R4S) Series

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