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Autoimmune Pancreatitis

An IgG4 Systemic Sclerosing Disease

Published: April 2013

Hot Topic Q&A is an opportunity for viewers to submit questions to the Hot Topic presenter. The opportunity to submit questions for this topic is now closed.

The following questions were submitted by viewers and answered by the presenters, Dora M. Lam-Himlin, MD, Senior Associate Consultant, Division of Anatomic Pathology, and Assistant Professor of Laboratory Medicine and Pathology at Mayo Clinic in Arizona.

Questions are presented as submitted (unedited).

  1. What amylase and lipase levels can be expected in the disease?

    Serum amylase and lipase are neither sensitive nor specific for autoimmune pancreatitis. Usually, their values are within normal limits or only mildly elevated.

1: Law R, Bronner M, Vogt D, Stevens T: Autoimmune pancreatitis: a mimic of pancreatic cancer. Cleve Clin J Med 2009 Oct;76(10):607-615 doi: 10.3949/ccjm.76a.09039. Review. PubMed PMID: 19797461.