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Guiding diagnosis and treatment of a complex disease

Updated: December 2014
Published: March 2013

Lymphoma Consultation Service

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Guiding Diagnosis and Treatment

Unless the reviewing pathologist has deep experience in lymphoma diagnosis, mistakes that result in incorrect, ineffective, and overly toxic therapies can easily be made. Lymphoma treatment also varies greatly among entities.

In fact, when patients who have had their lymphomas diagnosed at other institutions come to Mayo Clinic for treatment, the hematopathology group reviews the pathology materials that the patient brings with him/her. A recent review of this experience found that in 16% of cases, the diagnosis was revised in ways that made a large difference in the treatment recommendation for that patient.1

Mayo Clinic has a highly experienced, 9-member hematopathology section focusing on lymphoma diagnosis. They diagnose more than 3,000 lymphoma cases per year and have contributed more than 500 lymphoma-related articles to the peer-reviewed medical literature. They are also active participants in hematology and hematopathology professional societies; submitting abstracts and presenting continuing education courses on an ongoing basis.

To support hematopathology practices, Mayo Clinic utilizes:

  • Immunohistochemistry
  • Flow cytometry
  • Cytogenetics
  • Fluorescence in situ hybridization (FISH)
  • Molecular hematology assays
  • Mass spectrometry to aid in diagnosis.

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For More Information

For more information on how our testing can help with diagnose and guide treatment of lymphomas, contact your Mayo Medical Laboratories Regional Manager.


  1. Swapp R, Aubry M, Salomão D, Cheville J. Outside Case Review of Surgical Pathology for Referred Patients: The Impact on Patient Care. Arch Pathol Lab Med 2012 Jul 9. (Epub ahead of print)

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