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updated April 2012
Hematopoietic neoplasms are clonal disorders of hematopoietic cells, which constitute red cells, white cells, and platelets. They typically manifest as leukemias, lymphomas, and plasma cell disorders. Leukemias predominantly involve peripheral blood and bone marrow, while lymphomas involve tissue-based sites such as lymph nodes, stomach, or skin.
As technologies have advanced beyond typical chromosome analysis to include FISH- and PCR-based testing, accurate and cost-effective diagnosis of hematopoietic neoplasms has become much more challenging for clinicians and pathologists.
To address these challenges, Mayo Clinic clinicians and pathologists work together to establish unique test guidelines, algorithms, and specimen submission options that best utilize these technologies to provide the right diagnosis for the right patient.
These featured algorithms discuss diagnostic testing for myeloproliferative neoplasms:
These featured tests are the tests most frequently associated with hematopoietic neoplasms: