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Von Willebrand Disease

May 2013

Von Willebrand disease is the most common inherited bleeding condition, affecting males and females in approximately equal proportions in up to 1% of the United States and world populations. The cause is a deficiency in or dysfunction of von Willebrand factor, a plasma glycoprotein that enables platelets to adhere to sites of vascular injury and that also acts as a stabilizing protein for blood clotting factor VIII in the circulation.

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