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Disseminated Intravascular Coagulation (DIC)

May 2013

Disseminated intravascular coagulation, also known as intravascular coagulation and fibrinolysis (ICF), is a complex acquired syndrome that is always secondary to an underlying cause. It is characterized by activation of intravascular coagulation with secondary fibrinolysis or inhibited fibrinolysis.

The clinical presentation may include:

  • Thrombotic manifestations such as strokes and venous thromboembolism
  • Bleeding due to consumption of clotting factors and hyperfibrinolytic states

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