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Lysergic Acid Diethylamide (LSD)

Interpretation

  • The clearance half-life of LSD averages 3 hours, while the clearance half-life of LSD metabolite averages 12 hours.
  • The presence of LSD >LOQ indicates exposure to LSD within 1 day.
  • The presence of 2-oxo-3-hydroxy-LSD >LOQ indicates exposure to LSD within 2 to 5 days.

Metabolites

  • LSD is metabolized to 2-oxo-3-hydroxy-LSD.

    LSD 2-oxo-3-hydroxy-LSD

Approximate Detection Times

Lysergic Acid Diethylamide (LSD) LOQ (ng/mL) Detection Time* up to
     LSD
0.5
<1 day
     2-Oxo-3-hydroxy-LSD
5
5 days
*These are approximate detection times for the drug or metabolites in urine. The actual detection time depends on dose, frequency of use, and individual metabolism.

 


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