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Barbiturates

Interpretation

  • If there is a question as to a patient's therapeutic compliance, a serum test request for the specific drug of interest may be of help.

Metabolites

  • Mephobarbital is metabolized to phenobarbital.

    Mephobarbital Phenobarbital

Approximate Detection Times

Barbiturates LOQ (ng/mL) Detection Time* up to
     Long-Acting
          Phenobarbital
100
15 days
     Intermediate-Acting
          Butalbital
100
7 days
          Amobarbital
100
3 days
     Short-Acting
          Pentobarbital
100
3 days
          Secobarbital
100
3 days
*These are approximate detection times for the drug or metabolites in urine. The actual detection time depends on dose, frequency of use, and individual metabolism.


Key