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Biliary Tract Malignancy

Clinical Overview and Novel Detection Method



Related Video

For information on specimen collection and processing, see Biliary Tract Malignancy by FISH Testing.

Contact Dr. Gores

For questions regarding the management or treatment of a patient with this condition, contact Dr. Gores (Monday-Friday) at 507-284-6488.

Types of FISH Probes

Slide 12

September 2011

There are 2 basic types of FISH probes: chromosome enumeration probes and locus specific probes. Chromosome enumeration probes attach to the centromeres of chromosomes and are used to determine how many copies of a chromosome are present in a cell. Locus specific probes are designed to attach to genes of interest, for example the P16 tumor suppressor gene or the HER2 oncogene, and are used to determine if a cell shows deletion or amplification of those genes.

Types of FISH Probes

 


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