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Biliary Tract Malignancy

Clinical Overview and Novel Detection Method



Related Video

For information on specimen collection and processing, see Biliary Tract Malignancy by FISH Testing.

Contact Dr. Gores

For questions regarding the management or treatment of a patient with this condition, contact Dr. Gores (Monday-Friday) at 507-284-6488.

Primary Sclerosing Cholangitis (PSC)

Slide 4

September 2011

However, primary sclerosing cholangitis, abbreviated as PSC in this slide is a relatively common hepatobiliary disorder. It increases the risk of cholangiocarcinoma. This is a chronic inflammatory disorder involving the intra and extra hepatic bile ducts. It leads to biliary tract and hepatic fibrosis, biliary tract strictures, cholestasis, and cirrhosis.  PSC patients have a high risk of developing cholangiocarcinoma over their life time. Their lifetime risk is approximately 10% which is a 1000 fold greater risk than the general population. Most PSC patients are carefully followed for this potential complication by their hepatologist or gastroenterologist. If the cancer is found early, liver transplantation represents a chance for cure.

Primary Sclerosing Cholangitis (PSC)

 


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