Biliary Tract Malignancy

Pancreatobiliary Strictures (PBS)

September 2011

Pancreatobiliary strictures, abbreviated in this slide as PBS, are a common occurrence in clinical practice. Pancreatic biliary strictures may result from malignant or benign processes although malignant strictures are likely more common in clinical practice. Pancreatic cancer and cholangiocarcinoma are the most common etiologies of these strictures. It may be difficult to determine the difference between a small cancer in the head of the pancreas and a distal cholangiocarcinoma given their intimate anatomic association. The etiologies of these pancreatobiliary strictures are often unclear.

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Pancreatobiliary Strictures (PBS)

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Jump to section:

• Introduction
• Disclosures
• Pancreatobiliary Strictures (PBS)
• Primary Sclerosing Cholangitis (PSC)
• Pancreatobiliary Strictures (PBS)
• Bile Duct Brushings
• Current Clinical Practice
• Factors That Influence Sensitivity Of Cytology Specimens
• Routine Cytology
• Cancer Is A Genetic Disorder That Results From Mutations
• Detecting Tumor Cells in Cytology Specimens Using FISH
• Types of FISH Probes
• FISH
• Sensitivity and Specificity of Various Tests for Detection of Pancreatobiliary Strictures Malignancy
• What Do We Do With These Data?
• Bile Duct Pathology Calculator
• Representative Test Report Using Bile Duct Calculator
• Bile Duct Calculator
• Impact of Disease Prevalence on Positive Predictive Value (PPV)
• Case 1
• Case 1 Cytologic Findings
• Case 1
• Case 1 Test Report Using Bile Duct Calculator
• Case 1
• Case 1
• Case 2
• Case 2 Cytologic Findings
• Case 2
• Case 2: Test Report Using Bile Duct Calculator
• Case 2
• Case 2
• Case 3
• Case 3 Cytologic Findings
• Case 3
• Case 3
• Case 3: Test Report Using Bile Duct Calculator
• Case 3
• Case 3
• Summary
• Summary
• Results
• Questions?