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Biliary Tract Malignancy

Clinical Overview and Novel Detection Method

Related Video

For information on specimen collection and processing, see Biliary Tract Malignancy by FISH Testing.

Contact Dr. Gores

For questions regarding the management or treatment of a patient with this condition, contact Dr. Gores (Monday-Friday) at 507-284-6488.

Published: September 2011

Clinical Insight Q&A is an opportunity for viewers to submit questions to the Clinical Insight presenter. The opportunity to submit questions for this topic is now closed.

The following questions were submitted by viewers and answered by the presenters, Gregory Gores, MD and Kevin Halling, MD, PhD, both at Mayo Clinic in Rochester, Minnesota. Questions are presented as submitted (unedited).

  1. Are ERCP brushing evaluations only available at Mayo Clinic, or do other hospitals across the U.S. offer them as well?

    While other institutions are beginning to offer this testing, the assay was developed and validated at Mayo Clinic, giving us the most experience with the assay. In addition to this experience, we have performed extensive clinical validation using a large database of patients to correlate cytology and FISH results to clinical findings.

  2. May we send specimens for FISH for polysomy? What specimen do you prefer?

    Yes, we accept specimens for FISH testing (#19701 Biliary Tract Malignancy, FISH Only) which will be used to determine if there are polysomic or other chromosomally abnormal cells in the specimen. The specimen type that we prefer is ERCP brushing specimens placed in 20 mL PreservCyt of CytoLyt. We can offer alternatives if neither of these fixatives is available.