Test Algorithms

Algorithms provide guidance to appropriate ordering and use of laboratory tests. These algorithms are examples of diagnostic approaches recommended by physicians and laboratory experts at Mayo Clinic. The use of algorithms may reduce unnecessary testing and accelerate the diagnostic process.

Acylcarnitine Elevations—Newborn Screening Follow-up:

Newborn Screening Follow-up for Isolated C5 Acylcarnitine Elevations - UPDATED March 2009

Newborn Screening Follow-up for Elevations of C8, C6, and C10 Acylcarnitines - UPDATED March 2009

Newborn Screening Follow-up for Isolated C4 Acylcarnitine Elevations - UPDATED March 2009

Adulterant Survey Algorithm - New June 2009

Alpha1 Antitrypsin Genotyping - UPDATED January 2009

Amyloidosis: Laboratory Approach to the Diagnosis of Amyloidosis

Celiac Disease Testing Algorithm - UPDATED March 2009

Connective Tissue Diseases Cascade Test-Ordering Algorithm - UPDATED March 2009

Cystic Fibrosis Molecular Diagnostic Testing Algorithm

Fabry Disease Testing Algorithm - NEW June 2009

Familial Amyloidosis – Transthyretin Testing Algorithm

Familial/Autosomal Dominant Hypercholesterolemia Diagnostic Algorithm - REVIEWED 2009

Galactosemia Testing Algorithm

Helicobacter pylori Diagnostic Algorithm

Hepatitis Algorithms:

HBV:

HBV Infection-Diagnostic Approach and Management Algorithm - UPDATED June 2009

HBV Infection-Monitoring Before and After Liver Transplantation - UPDATED June 2009

HCV:

Recommended Approach to the Diagnosis, Monitoring, and Treatment of Patients with Hepatitis C Virus - UPDATED March 2009

Alternative Approaches to the Diagnosis and Monitoring of Patients with Hepatitis C Virus - UPDATED April 2009

Hepatitis C Virus Treatment Algorithm - UPDATED March 2009

Hereditary Colorectal Cancer Algorithms:

Colonic Adenomatous Polyposis Syndromes Testing Algorithm

Hereditary Nonpolyposis Colorectal Cancer Testing Algorithm

Hereditary Hemochromatosis Algorithm - REVIEWED 2009

HIV Algorithms:

HIV Serologic Screening Algorithm (excludes HIV rapid testing) - UPDATED January 2009

HIV Rapid Serology Follow-up Algorithm - UPDATED January 2009

HIV Treatment Monitoring Algorithm - UPDATED September 2008

Myasthenia Gravis Algorithms:

Myasthenia Gravis: Adult Diagnostic Algorithm

Myasthenia Gravis/Lambert Eaton Syndrome Diagnostic Algorithm

Myasthenia Gravis: Pediatric Diagnostic Algorithm

Myasthenia Gravis: Thymoma Diagnostic Algorithm

Multiple Myeloma: An Expanded Algorithm for the Laboratory Evaluation of Suspected Multiple Myeloma - REVIEWED 2009

Pancreatic Cyst Fluid Markers – Interpretive Algorithm - NEW March 2009

Paraneoplastic Evaluation Algorithm- UPDATED July 2008

Parasitic Investigation of Stool Specimens - UPDATED December 2008

Pernicious Anemia Testing Algorithm - REVIEWED 2009

Porphyrias:

Porphyria (Acute) Testing Algorithm - UPDATED March 2009

Porphyria (Cutaneous) Testing Algorithm - UPDATED March 2009

Postmortem Screening Algorithm

Prader-Willi and Angelman Syndromes: Laboratory Approach to Diagnosis - UPDATED January 2009

Tay-Sachs Disease Carrier Testing Protocol

Thyroid Function Ordering Algorithm - UPDATED March 2009

Wilson Disease Testing Algorithm - UPDATED June 2009

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Mayo Medical Laboratories algorithms are designed to assist in the investigation and monitoring of disease in the most logical, cost-effective approach. The information in these algorithms is based on Mayo test validation information and may not apply to similar tests developed or performed elsewhere. These algorithms are intended to be used in conjunction with clinical judgment, based on the clinical presentation of the patient.