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Test Algorithms

Algorithms provide guidance to appropriate ordering and use of laboratory tests. These algorithms are examples of diagnostic approaches recommended by physicians and laboratory experts at Mayo Clinic. The use of algorithms may reduce unnecessary testing and accelerate the diagnostic process.

Abacavir Hypersensitivity Testing and Initial Patient Management Algorithm - New January 2010
Acylcarnitine Elevations—Newborn Screening Follow-up:
Newborn Screening Follow-up for Isolated C5 Acylcarnitine Elevations - Reviewed July 2010
Newborn Screening Follow-up for Elevations of C8, C6, and C10 Acylcarnitines - Reviewed May 2010
Newborn Screening Follow-up for Isolated C4 Acylcarnitine Elevations - Reviewed July 2010
Adulterant Survey Algorithm - Reviewed June 2010
Alpha1 Antitrypsin Genotyping - Reviewed June 2010
Amyloidosis
Amyloidosis: Laboratory Approach to the Diagnosis of Amyloidosis - Reviewed July 2010
Familial Amyloidosis – Transthyretin Testing Algorithm - Reviewed May 2010
Autoimmune Dysautonomia Evaluation Testing Algorithm - New July 2010
Autoimmune Gastrointestinal Dysmotility Evaluation Testing Algorithm - New July 2010
Celiac Disease Algorithms:
Celiac Disease Comprehensive Cascade - New April 2010
Celiac Disease Diagnostic Testing Algorithm - Reviewed April 2010
Celiac Disease Comprehensive Cascade for Patients on a Gluten-Free Diet - New April 2010
Celiac Disease Serology Cascade - Reviewed May 2010
Celiac Disease Routine Treatment Monitoring Algorithm - New April 2010
Connective Tissue Diseases Cascade Test-Ordering Algorithm - Updated March 2009
Cystic Fibrosis Molecular Diagnostic Testing Algorithm - Reviewed June 2010
Fabry Disease Testing Algorithm - - Reviewed June 2010
Familial/Autosomal Dominant Hypercholesterolemia Diagnostic Algorithm - Reviewed May 2010
Galactosemia Testing Algorithm - Updated February 2010
Helicobacter pylori Diagnostic Algorithm - Reviewed July 2010
Hepatitis Algorithms:
HBV:
HBV Infection-Diagnostic Approach and Management Algorithm - Updated January 2010
HBV Infection-Monitoring Before and After Liver Transplantation - Updated December 2009
HCV:
Recommended Approach to the Diagnosis, Monitoring, and Treatment of Patients with Hepatitis C Virus - Reviewed May 2010
Alternative Approaches to the Diagnosis and Monitoring of Patients with Hepatitis C Virus - Reviewed May 2010
Hepatitis C Virus Treatment Algorithm - Updated March 2009
Hereditary Colorectal Cancer Algorithms:
Colonic Adenomatous Polyposis Syndromes Testing Algorithm
Hereditary Nonpolyposis Colorectal Cancer Testing Algorithm - Reviewed June 2010
Hereditary Hemochromatosis Algorithm - - Reviewed June 2010
HIV Algorithms:
HIV Serologic Screening Algorithm (excludes HIV rapid testing) - Updated May 2010
HIV Rapid Serology Follow-up Algorithm - Updated May 2010
HIV Treatment Monitoring Algorithm - Updated May 2010
Myasthenia Gravis Algorithms:
Myasthenia Gravis: Adult Diagnostic Algorithm - Reviewed June 2010
Myasthenia Gravis/Lambert Eaton Syndrome Diagnostic Algorithm - Updated June 2010
Myasthenia Gravis: Pediatric Diagnostic Algorithm - Reviewed June 2010
Myasthenia Gravis: Thymoma Diagnostic Algorithm - Reviewed June 2010
Multiple Myeloma: Laboratory Screening Tests for Suspected Multiple Myeloma - Updated July 2010
Paraneoplastic Evaluation Algorithm- Updated June 2010
Parasitic Investigation of Stool Specimens - Updated June 2010
Pernicious Anemia Testing Cascade - Reviewed May 2010
Porphyrias:
Porphyria (Acute) Testing Algorithm - Reviewed June 2010
Porphyria (Cutaneous) Testing Algorithm -Reviewed June 2010
Postmortem Screening Algorithm - Reviewed May 2010
Prader-Willi and Angelman Syndromes: Laboratory Approach to Diagnosis - Reviewed June 2010
Steroid Pathway - New June 2010
Transfusion Algorithms:
Intensive Care Unit (ICU) Transfusion Algorithm -Reviewed July 2010
Operating Room Transfusion Algorithm - Reviewed July 2010
Tay-Sachs Disease Carrier Testing Protocol - Updated May 2010
Thyroid Function Ordering Algorithm - Reviewed May 2010
UGT1A1 Test-Ordering Algorithm - New April 2010
Wilson Disease Testing Algorithm - - Reviewed June 2010

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Mayo Medical Laboratories algorithms are designed to assist in the investigation and monitoring of disease in the most logical, cost-effective approach. The information in these algorithms is based on Mayo test validation information and may not apply to similar tests developed or performed elsewhere. These algorithms are intended to be used in conjunction with clinical judgment, based on the clinical presentation of the patient.